If your proxies are replaced frequently, either through auto-replacements or auto-refreshes, we recommend using the proxies in Backbone Connection.
If you authenticate the proxies using username/password, then the username will be the distinguishing factor (e.g. username-1, username-2, etc.), and the assigned IP addresses will change without disrupting your connections.
If you authenticate the proxies using IP authorization, then the ports will be the distinguishing factor (e.g. 10000, 10001, etc.), and the assigned IP addresses will change without interrupting your connections.